Article
Sitafloxacin activity against Helicobacter pylori isolates, including those with gyrA mutations.
Antimicrobial agents and chemotherapy - 1 Jul 2009
Murakami Kazunari, Okimoto Tadayoshi, Kodama Masaaki, Tanahashi Jin, Fujioka Toshio, Ikeda Fumiaki, Muraoka Hiroe, Takigawa Motoko, Saika Takeshi, Hasegawa Miyuki, Kobayashi Intetsu
Abstract excerpt
Sitafloxacin showed MICs of less than or equal to 0.5 microg/ml against 105 isolates of Helicobacter pylori, including 44 isolates with mutations in the gyrA gene. The highest MICs for garenoxacin and levofloxacin were 8 and 64 times, respectively, higher than the highest MICs observed for sitafloxacin.
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