Article
Efficacy of sitafloxacin-based rescue therapy for Helicobacter pylori after failures of first- and second-line therapies.
Antimicrobial agents and chemotherapy - 1 Mar 2012
Matsuzaki Juntaro, Suzuki Hidekazu, Nishizawa Toshihiro, Hirata Kenro, Tsugawa Hitoshi, Saito Yoshimasa, Okada Sawako, Fukuhara Seiichiro, Hibi Toshifumi
Abstract excerpt
Sitafloxacin-based triple therapy achieved 83.6% (per-protocol) and 78.2% (intention-to-treat) success in eradicating Helicobacter pylori among 78 Japanese patients after clarithromycin-based first-line and metronidazole-based second-line triple therapies failed. Eradication succeeded in 32 out of 43 patients, even with gyrA mutation-positive Helicobacter pylori (per protocol). The position of the gyrA mutation...
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