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Article

Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations.

Journal of hepatology - 1 Jun 2009

Tanaka Atsushi, Nezu Saeko, Uegaki Satoko, Kikuchi Kentaro, Shibuya Akitaka, Miyakawa Hiroshi, Takahashi Shin-ichi, Bianchi Ilaria, Zermiani Paola, Podda Mauro, Ohira Hiromasa, Invernizzi Pietro, Takikawa Hajime

Abstract excerpt

BACKGROUND/AIMS: Vitamin D receptor (VDR) agonists have recently been identified as potent immunomodulators capable of inhibiting Th1-mediated immune response, leading us to consider the hypothesis that functional VDR polymorphisms might contribute to enhanced risk for developing primary biliary cirrhosis (PBC), a Th1-mediated autoimmune disease. In the current study, we aimed at elucidating the genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19376604
DOI: 10.1016/j.jhep.2009.01.015

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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