Article
Multiple acquisitions of CTX-M plasmids in the rare D2 genotype of Escherichia coli provide evidence for convergent evolution.
Microbiology (Reading, England) - 1 May 2009
Deschamps Catherine, Clermont Olivier, Hipeaux Marie Claire, Arlet Guillaume, Denamur Erick, Branger Catherine
Abstract excerpt
Over the last decade, CTX-M enzymes have become the most prevalent extended-spectrum beta-lactamases (ESBLs) worldwide, mostly in Escherichia coli, causing a major health problem. An epidemiological relationship has been established between a rare genotype of E. coli, the D(2) genotype, and the presence of CTX-M genes. We investigated this striking association by exploring the genetic backgrounds of 18 D(2)...
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