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Effect of mono‐(2‐ethylhexyl) phthalate (MEHP) on resumption of meiosis, <i>in vitro</i> maturation and embryo development of immature mouse oocytes

1 Jan 2008

Abstract excerpt

The purpose of this study was to evaluate the effect of MEHP on in vitro maturation of mouse oocytes and resulting embryo development. Denuded oocytes (DO) were cultured in maturation medium supplemented with 0, 50, 100, 200 and 400 microM levels of MEHP for 24 h. The matured oocytes then were fertilized and cultured for 4 days. The percentage of Germinal Vesicle (GV) stage oocytes were significantly higher in...

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PMID: 19346590
DOI: 10.1002/biof.5520330207

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