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Article

Serial monitoring of T315I BCR-ABL mutation by Invader assay combined with RT-PCR.

International journal of hematology - 1 May 2009

Yamamoto Masahide, Kakihana Kazuhiko, Ohashi Kazuteru, Yamaguchi Toshikazu, Tadokoro Kenichi, Akiyama Hideki, Sakamaki Hisashi

Abstract excerpt

We recently developed an Invader assay combined with reverse transcriptase polymerase-chain-reaction in order to quantify T315I bcr-abl transcripts. Using this assay, we serially monitored T315I bcr-abl transcripts in chronic myeloid leukemia (CML) patients whose bcr-abl transcripts were still detectable at 6 months after starting imatinib therapy. Although, we continued to monitor bcr-abl transcripts in 14 CML...

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Source

Identifiers

PMID: 19343480
DOI: 10.1007/s12185-009-0290-9

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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