Article
The COUP-adjacent repressor (CAR) element participates in the tissue-specific expression of the ovalbumin gene.
Biochimica et biophysica acta - 15 Dec 2000
Monroe D G, Sanders M M
Abstract excerpt
The ovalbumin (Ov) gene is an excellent model for the study of tissue-specific gene regulation as it is only active in the estrogen-stimulated oviduct. Previous studies have demonstrated that the negative regulatory element (NRE) in the Ov gene 5'-flanking region is responsible for silencing the gene in oviduct in the absence of steroids. Linker scanning analysis defined an element within the NRE designated the...
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