Article
Altered lymphocyte populations in sphha/sphha mice with chronic hemolytic anemia.
Cellular immunology - 1 Dec 1991
Maggio-Price L, Grossmann A, Engel D, Rosse C
Abstract excerpt
Lymphocyte kinetics and phenotype were examined in mutant anemic sphha/sphha mice that manifest a lifelong lymphocytosis which accompanies their chronic hemolytic anemia. Anemic mice have significant increases in CD4+, CD8+, and sIgM+ lymphocytes in peripheral blood. Pulse and continuous infusion studies with [3H]TdR suggest that this apparent lymphoid expansion is not due to increased production of lymphocytes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
