Article
Altered lymphocyte populations in sphha/sphha mice with chronic hemolytic anemia.
Cellular immunology - 1 Dec 1991
Maggio-Price L, Grossmann A, Engel D, Rosse C
Abstract excerpt
Lymphocyte kinetics and phenotype were examined in mutant anemic sphha/sphha mice that manifest a lifelong lymphocytosis which accompanies their chronic hemolytic anemia. Anemic mice have significant increases in CD4+, CD8+, and sIgM+ lymphocytes in peripheral blood. Pulse and continuous infusion...
Topics
- Anemia, Hemolytic, Congenital
- Animals
- Bone Marrow Cells
- Cell Division
- Chronic Disease
- Leukocyte Count
- Lymph Nodes
- Lymphocyte Subsets
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Phenotype
- Spectrin
- Spleen
- T-Lymphocytes