Article
Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes.
The British journal of psychiatry : the journal of mental science - 1 Apr 2009
Lencz Todd, Lipsky Robert H, DeRosse Pamela, Burdick Katherine E, Kane John M, Malhotra Anil K
Abstract excerpt
BACKGROUND: Allelic variation in the gene encoding brain-derived neurotrophic factor (BDNF) has been associated with affective disorders, but generally not schizophrenia. Brain-derived neurotrophic factor variants may help clarify the status of schizoaffective disorder. AIMS: To test the hypothesis that BDNF haplotypes are associated with psychiatric illness marked by a prominent affective component. METHOD:...
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