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Article

Transcription regulation of restriction-modification system Esp1396I.

Nucleic acids research - 1 Jun 2009

Bogdanova Ekaterina, Zakharova Marina, Streeter Simon, Taylor James E N, Heyduk Tomasz, Kneale Geoff, Severinov Konstantin

Abstract excerpt

The convergently transcribed restriction (R) and methylase (M) genes of the Restriction-Modification system Esp1396I are tightly regulated by a controller (C) protein that forms part of the CR operon. We have mapped the transcriptional start sites from each promoter and examined the regulatory role of C.Esp1396I in vivo and in vitro. C-protein binding at the CR and M promoters was analyzed by DNA footprinting and...

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Identifiers

PMID: 19336410
DOI: 10.1093/nar/gkp210
PMCID: PMC2691842

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Source receipt: pubmed, retrieved 7 Sept 2026.

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