Article
Clinical and molecular neuroimaging characteristics of Brazilian patients with Parkinson's disease and mutations in PARK2 or PARK8 genes.
Arquivos de neuro-psiquiatria - 1 Mar 2009
Barsottini Orlando G P, Felício Andre C, Aguiar Patricia de Carvalho, Godeiro-Junior Clecio, Shih Ming C, Hoexter Marcelo Q, Bressan Rodrigo A, Ferraz Henrique B, Andrade Luiz Augusto F
Abstract excerpt
OBJECTIVE: To describe clinical and neuroimaging (SPECT) characteristics of Brazilian patients with Parkinson's disease (PD) and mutations in PARK2 or PARK8 genes. METHOD: A total of 119 patients meeting clinical criteria for PD were evaluated. RESULTS: Of all patients studied, 13 had mutations in either PARK2 (n=9) or PARK8 genes (n=4). No statistically significant differences in clinical characteristics in both...
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