Article
Detection of circulating fetal nucleic acids: a review of methods and applications.
Journal of clinical pathology - 1 Apr 2009
Hung E C W, Chiu R W K, Lo Y M D
Abstract excerpt
The discovery of cell-free circulating fetal nucleic acids in maternal plasma has opened up new possibilities in non-invasive prenatal diagnosis. The rapid advancement of this field in the past decade is catalysed by the discovery of new classes of fetal nucleic acid markers and technological developments in nucleic acid detection and amplification. In this review, some of the more significant recent developments...
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