Article
Indole acts as an extracellular cue regulating gene expression in Vibrio cholerae.
Journal of bacteriology - 1 Jun 2009
Mueller Ryan S, Beyhan Sinem, Saini Simran G, Yildiz Fitnat H, Bartlett Douglas H
Abstract excerpt
Indole has been proposed to act as an extracellular signal molecule influencing biofilm formation in a range of bacteria. For this study, the role of indole in Vibrio cholerae biofilm formation was examined. It was shown that indole activates genes involved in vibrio polysaccharide (VPS) production, which is essential for V. cholerae biofilm formation. In addition to activating these genes, it was determined...
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