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Article

Structural rearrangements and the unfolding mechanism of a Trigger Factor mutant studied by multiple structural probes.

Biochimica et biophysica acta - 1 Jun 2009

Fan Dong-Jie, Ding Yan-Wei, Zhou Jun-Mei

Abstract excerpt

Trigger Factor (TF) is a three-domain chaperone which catalyzes nascent peptide folding and harbors peptidyl-prolyl cis-trans isomerase activity. The multi-domain structure of TF makes it an interesting and challenging candidate for studies of the structural properties and functional behavior of individual domains or combined domain constructs. Here we constructed a TF mutant, NC, combining the N- and C-domains...

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Identifiers

PMID: 19328871
DOI: 10.1016/j.bbapap.2009.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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