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Article

Variants in the HMG-CoA reductase (HMGCR) gene influence component phenotypes in polycystic ovary syndrome.

Fertility and sterility - 1 Jun 2010

Xu Ning, Taylor Kent D, Azziz Ricardo, Goodarzi Mark O

Abstract excerpt

OBJECTIVE: To study the role of genetic variation in the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGCR) gene in polycystic ovary syndrome (PCOS). DESIGN: Women with and without PCOS were genotyped for seven single-nucleotide polymorphisms (SNPs) in HMGCR. The SNPs and haplotypes were determined and tested for association with PCOS and its component traits. SETTING: Subjects were recruited from...

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Share to Adolescent
Share to Genetic Linkage
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl CoA Reductases

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Share to Polymorphism, Single Nucleotide

Share to Sex Hormone-Binding Globulin

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Source

Open in PubMed Open full text

Identifiers

PMID: 19327767
DOI: 10.1016/j.fertnstert.2009.01.158
PMCID: PMC3032056

Genes

HMGCR
SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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