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Renibacterium salmoninarum p57 antigenic variation is restricted in geographic distribution and correlated with genomic markers.

Diseases of aquatic organisms - 12 Feb 2009

Wiens Gregory D, Dale Ole Bendik

Abstract excerpt

The 57 kDa protein (p57) is an important diagnostic antigen that is implicated in the pathogenesis of salmonid bacterial kidney disease. Little is known about the nature and extent of antigenic variation in p57. Previously, we reported that p57 produced by Renibacterium salmoninarum Strain 684 contains a mutation that disrupts monoclonal antibody (MAb) 4C11 binding. In the present study, we examined MAb binding...

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PMID: 19326793
DOI: 10.3354/dao01986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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