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Article

Both msa genes in Renibacterium salmoninarum are needed for full virulence in bacterial kidney disease.

Applied and environmental microbiology - 1 Apr 2006

Coady Alison M, Murray Anthony L, Elliott Diane G, Rhodes Linda D

Abstract excerpt

Renibacterium salmoninarum, a gram-positive diplococcobacillus that causes bacterial kidney disease among salmon and trout, has two chromosomal loci encoding the major soluble antigen (msa) gene. Because the MSA protein is widely suspected to be an important virulence factor, we used insertion-duplication mutagenesis to generate disruptions of either the msa1 or msa2 gene. Surprisingly, expression of MSA protein...

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Identifiers

PMID: 16597972
DOI: 10.1128/AEM.72.4.2672-2678.2006
PMCID: PMC1449061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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