Article
Frequent occurrence of <i>RASSF1A</i> promoter hypermethylation and merkel cell polyomavirus in merkel cell carcinoma
26 Mar 2009
Abstract excerpt
Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. It has recently been reported that integration of a Merkel cell polyomavirus (MCPyV) in receptor tyrosine phosphates type G (PTPRG) gene occurs in MCC, and that viral infections are associated with epigenetic silencing of tumor suppressor genes (TSG) in cancer. To examine whether a correlation between TSG inactivation and viral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
