Article
Circulating HIV type 1 drug resistance will have limited impact on the effectiveness of preexposure prophylaxis among young women in Zimbabwe.
The Journal of infectious diseases - 1 May 2009
van de Vijver David A M C, Derdelinckx Inge, Boucher Charles A B
Abstract excerpt
BACKGROUND: Preexposure prophylaxis (PrEP) with antiretroviral drugs may prevent transmission of human immunodeficiency virus (HIV). Our objective was to predict whether PrEP, in the presence of circulating drug resistance, will reduce the risk of infection with HIV. METHODS: We used risk equations to calculate the monthly risk of infection with HIV before and after the introduction of PrEP. Uncertainty and...
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