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Article

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.

The Journal of clinical endocrinology and metabolism - 1 Jul 2006

Böttcher Yvonne, Teupser Daniel, Enigk Beate, Berndt Janin, Klöting Nora, Schön Michael R, Thiery Joachim, Blüher Matthias, Stumvoll Michael, Kovacs Peter

Abstract excerpt

CONTEXT AND OBJECTIVE: Visfatin is a peptide suggested to play a role in glucose homeostasis. In the present study, we investigated the role of genetic variation in the visfatin gene in the pathophysiology of obesity/type 2 diabetes mellitus (T2DM). DESIGN: The visfatin gene (PBEF1) was sequenced in DNA samples from 24 nonrelated Caucasian subjects. Identified genetic variants were used for association analyses...

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PMID: 16636125
DOI: 10.1210/jc.2006-0149

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Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.PMID 16636125Read ↗

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