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Article

Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum

1 Jan 2009

Abstract excerpt

BACKGROUND: Proteolytic Clostridium botulinum is the causative agent of botulism, a severe neuroparalytic illness. Given the severity of botulism, surprisingly little is known of the population structure, biology, phylogeny or evolution of C. botulinum. The recent determination of the genome sequence of C. botulinum has allowed comparative genomic indexing using a DNA microarray. RESULTS: Whole genome microarray...

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PMID: 19298644
DOI: 10.1186/1471-2164-10-115

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