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Article

A rapid detection method for the ryanodine receptor 1 (C7360G) mutation in Quarter Horses.

Journal of veterinary internal medicine - 1 Jan 2000

Nieto J E, Aleman M

Abstract excerpt

BACKGROUND: Anesthetic-induced malignant hyperthermia has been documented in Quarter Horses and is caused by a single-point mutation in the ryanodine receptor 1 gene at nucleotide C7360G generating a R2454G amino acid substitution. An accurate, faster molecular test that is less prone to contamination would facilitate screening for the mutation in horses intended for breeding, in those undergoing surgical...

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Identifiers

PMID: 19298609
DOI: 10.1111/j.1939-1676.2009.0281.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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