Article
New test for endothelin receptor type B (EDNRB) mutation genotyping in horses.
Molecular and cellular probes - 1 Jun 2016
Ayala-Valdovinos Miguel Angel, Galindo-García Jorge, Sánchez-Chiprés David, Duifhuis-Rivera Theodor
Abstract excerpt
Lethal white foal syndrome (LWFS) is an autosomal recessive disease of neonatal foals characterized by a white hair coat and a functional intestinal obstruction. Traditional techniques for identifying the dinucleotide mutation (TC→AG) of the endothelin receptor B gene (EDNRB) associated with LWFS are time-consuming. We developed a new technique based on mutagenically separated polymerase chain reaction (MS-PCR)...
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