Article
Early prediction of sustained virological response at day 3 of treatment with albinterferon-alpha-2b in patients with genotype 2/3 chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2009
Neumann Avidan U, Bain Vincent G, Yoshida Eric M, Patel Keyur, Pulkstenis Erik, Subramanian G Mani
Abstract excerpt
BACKGROUND: Albinterferon-alpha-2b (albIFN) is a long-acting fusion polypeptide composed of albumin and IFN-alpha-2b. In a phase 2 study of albIFN 1500 mug q2wk or q4wk in patients with genotype 2/3 chronic hepatitis C, albIFN demonstrated sustained virological response (SVR) rates of 62-77% (intent-to-treat population). AIMS: To assess the association of initial viral kinetics during albIFN therapy with baseline...
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