Article
Albinterferon alfa-2b dosed every two or four weeks in interferon-naïve patients with genotype 1 chronic hepatitis C.
Hepatology (Baltimore, Md.) - 1 Aug 2008
Zeuzem Stefan, Yoshida Eric M, Benhamou Yves, Pianko Stephen, Bain Vincent G, Shouval Daniel, Flisiak Robert, Rehak Vratislav, Grigorescu Mircea, Kaita Kelly, Cronin Patrick W, Pulkstenis Erik, Subramanian G Mani, McHutchison John G
Abstract excerpt
UNLABELLED: The efficacy and safety of albinterferon alfa-2b (alb-IFN), a novel recombinant protein consisting of interferon alfa-2b genetically fused to human albumin, was evaluated in a phase 2b, open-label study of patients with genotype 1, chronic hepatitis C. In all, 458 IFN-alfa treatment-naïve patients were randomized to 48-week treatment with peginterferon alfa (PEG-IFNalpha)-2a 180 microg one time per...
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