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Article

The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa.

FEMS microbiology letters - 1 May 2009

Sanders Laurie H, Sudhakaran Julee, Sutton Mark D

Abstract excerpt

Inactivation of the Pseudomonas aeruginosa mutM, mutY, or mutT gene conferred a 2.4-, 17.2-, or 38.1-fold increase in spontaneous mutation frequency, respectively. Importantly, the mutY and mutT strains each displayed a robust H(2)O(2)-induced mutation frequency. In addition, the mutM, mutY, and mutT mutations severely sensitized P. aeruginosa to killing by H(2)O(2), suggesting that these gene products act to...

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Identifiers

PMID: 19291074
DOI: 10.1111/j.1574-6968.2009.01550.x
PMCID: PMC2863324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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