Article
Quantitative immunocytochemical profile to predict early outcome of disease in triple-negative breast carcinomas.
International journal of oncology - 1 Apr 2009
Charpin Colette, Giusiano Sophie, Secq Véronique, Carpentier Séverine, Andrac Lucile, Lavaut Marie-Noëlle, Allasia Claude, Bonnier Pascal, Garcia Stéphane
Abstract excerpt
We aimed in this study at identifying prognostic immunohistochemical molecular signatures indicative of disease outcome, also relevant for development of new specific therapies, in triple-negative (ER, PR, c-erbB2- negative) breast carcinoma subtypes. We evaluated 42 markers in tissue micro-arrays from a series of 924 breast carcinomas including 184 triple-negative tumors using standardized quantitative...
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