Article
Genetic and expression alterations in association with the sarcomatous change of cholangiocarcinoma cells.
Experimental & molecular medicine - 28 Feb 2009
Yoo Hee-Jung, Yun Bo-Ra, Kwon Jung-Hee, Ahn Hyuk-Soo, Seol Min-A, Lee Mi-Jin, Yu Goung-Ran, Yu Hee-Chul, Hong BeeHak, Choi KwanYong, Kim Dae-Ghon
Abstract excerpt
Cholangiocarcinoma (CC) is an intrahepatic bile duct carcinoma with a high mortality rate and a poor prognosis. Sarcomatous change/epithelial mesenchymal transition (EMT) of CC frequently leads to aggressive intrahepatic spread and metastasis. The aim of this study was to identify the genetic alterations and gene expression pattern that might be associated with the sarcomatous change in CC. Previously, we...
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