Article
Cellular adaptation during chronic neonatal hypoxic pulmonary hypertension.
The American journal of physiology - 1 Oct 1991
Stenmark K R, Aldashev A A, Orton E C, Durmowicz A G, Badesch D B, Parks W C, Mecham R P, Voelkel N F, Reeves J T
Abstract excerpt
Newborn animals develop more severe hypoxic pulmonary hypertension than do adults, their vascular changes are greater, and both the hypertension and vascular changes occur more rapidly. We hypothesize that this differential developmentally controlled response may arise from either a difference in...
Topics
- Animals
- Animals, Newborn
- Blood Pressure
- Cell Division
- Chronic Disease
- Extracellular Matrix Proteins
- Humans
- Hypertension, Pulmonary
- Hypoxia
- Phenotype
- Pulmonary Artery