Article
CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.
Cancer research - 15 Mar 2009
Aldrich Melinda C, Selvin Steve, Hansen Helen M, Barcellos Lisa F, Wrensch Margaret R, Sison Jennette D, Kelsey Karl T, Buffler Patricia A, Quesenberry Charles P, Seldin Michael F, Wiencke John K
Abstract excerpt
Prior studies of lung cancer and CYP1A1/2 in African-American and Latino populations have shown inconsistent results and have not yet investigated the haplotype block structure of CYP1A1/2 or addressed potential population stratification. To investigate haplotypes in the CYP1A1/2 region and lung cancer in African-Americans and Latinos, we conducted a case-control study (1998-2003). African-Americans (n = 535) and...
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