Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction.

The Journal of clinical endocrinology and metabolism - 1 May 2009

McCarthy Jeanette J, Somji Aleefia, Weiss Lauren A, Steffy Brian, Vega Raquel, Barrett-Connor Elizabeth, Talavera Gregory, Glynne Richard

Abstract excerpt

BACKGROUND: Genetic variation in diabetes-associated genes cumulatively explain little of the overall heritability of this trait. We sought to determine whether polymorphisms of the scavenger receptor class B, member I (SCARB1), an estrogen-regulated chromosome 12q24 positional candidate diabetes gene, were associated with type 2 diabetes or insulin resistance in a sex-specific fashion. METHODS: We evaluated 34...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Homeostasis

Share to Insulin Resistance

Share to Mexican Americans

Share to Scavenger Receptors, Class B

Share to Sex Characteristics

Source

Open in PubMed Open full text

Identifiers

PMID: 19276229
DOI: 10.1210/jc.2008-2800
PMCID: PMC2684479

Genes

SCARB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction.PMID 19276229Read ↗

Scavenger Receptor Class B Type 1 Gene Polymorphism as a Possible Genetic Risk Factor for Insulin resistanceSemantic proximity Read ↗

Variants in scavenger receptor class B type I gene are associated with HDL cholesterol levels in younger women.Semantic proximity Read ↗

A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet.Semantic proximity Read ↗

Expression Levels and Genetic Polymorphism of Scavenger Receptor Class B Type 1 as a Biomarker of Type 2 Diabetes Mellitus.Semantic proximity Read ↗

Impact of genetic variants in human scavenger receptor class B type I (SCARB1) on plasma lipid traits.Semantic proximity Read ↗

Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.Semantic proximity Read ↗

Genetic variation at the scavenger receptor class B type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the framingham study.Semantic proximity Read ↗

Association of the Lipoprotein Receptor SCARB1 Common Missense Variant rs4238001 with Incident Coronary Heart Disease.Semantic proximity Read ↗

Scavenger receptor class B type I polymorphisms and peripheral arterial disease.Semantic proximity Read ↗

The SCARB1 gene is associated with lipid response to dietary and pharmacological interventions.Semantic proximity Read ↗

Insulin receptor substrate 1 (IRS1) variants confer risk of diabetes in the Boston Puerto Rican Health Study.Semantic proximity Read ↗

Association of scavenger receptor class B type I polymorphisms with subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.