Article
Structure of a viral cap-independent translation element that functions via high affinity binding to the eIF4E subunit of eIF4F.
The Journal of biological chemistry - 22 May 2009
Wang Zhaohui, Treder Krzysztof, Miller W Allen
Abstract excerpt
RNAs of many positive strand RNA viruses lack a 5' cap structure and instead rely on cap-independent translation elements (CITEs) to facilitate efficient translation initiation. The mechanisms by which these RNAs recruit ribosomes are poorly understood, and for many viruses the CITE is unknown. Here we identify the first CITE of an umbravirus in the 3'-untranslated region of pea enation mosaic virus RNA 2....
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