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Article

ABCG2-mediated DyeCycle Violet efflux defined side population in benign and malignant prostate

1 Apr 2009

Abstract excerpt

The efflux of Hoechst 33342 by ATP-binding cassette protein G2 (ABCG2) membrane pump allows reproducible identification of a subpopulation of cells by flow cytometric analysis termed the "side population" (SP). The SP identified by constitutive Hoechst efflux contains the stem/progenitor cell population from bone marrow and many solid organs, including prostate. DyeCycle Violet (DCV) is a cell membrane permeable,...

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PMID: 19270533
DOI: 10.4161/cc.8.7.8043

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ABCG2-mediated DyeCycle Violet efflux defined side population in benign and malignant prostatePMID 19270533Read ↗

Harnessing the DNA Dye-triggered Side Population Phenotype to Detect and Purify Cancer Stem Cells from Biological Samples.Semantic proximity Read ↗

Hoechst 33342 side population identification is a conserved and unified mechanism in urological cancers.Semantic proximity Read ↗

Molecular and cellular characterization of ABCG2 in the prostateSemantic proximity Read ↗

Kinetic analysis of intracellular Hoechst 33342--DNA interactions by flow cytometry: misinterpretation of side population status?Semantic proximity Read ↗

Aldehyde dehydrogenase and ATP binding cassette transporter G2 (ABCG2) functional assays isolate different populations of prostate stem cells where ABCG2 function selects for cells with increased stem cell activitySemantic proximity Read ↗

Identification of side population cells from bladder cancer cells by DyeCycle Violet staining.Semantic proximity Read ↗

Novel method for the isolation and characterisation of the putative prostatic stem cell.Semantic proximity Read ↗

Critical appraisal of the side population assay in stem cell and cancer stem cell research.Semantic proximity Read ↗

Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer CellsSemantic proximity Read ↗

Side Population: Its Use in the Study of Cellular Heterogeneity and as a Potential Enrichment Tool for Rare Cell PopulationsSemantic proximity Read ↗

Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice.Semantic proximity Read ↗

Side Population Is Enriched in Tumorigenic, Stem-Like Cancer Cells, whereas ABCG2+ and ABCG2− Cancer Cells Are Similarly TumorigenicSemantic proximity Read ↗

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