Article
Genetic and pharmacokinetic factors affecting the initial pharmacotherapeutic effect of paroxetine in Japanese patients with panic disorder.
European journal of clinical pharmacology - 1 Jul 2009
Saeki Yoshinori, Watanabe Takashi, Ueda Mikito, Saito Atsushi, Akiyama Kazufumi, Inoue Yoshimasa, Hirokane Genta, Morita Sachiyo, Yamada Naoto, Shimoda Kazutaka
Abstract excerpt
OBJECTIVE: The objective of this study was to evaluate genetic and pharmacokinetic factors affecting the initial pharmacotherapeutic effect of paroxetine (PAX) in Japanese patients with panic disorder (PD). METHOD: Plasma concentration of PAX was determined by high performance liquid chromatograp...
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