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Quality of Life in Patients with Leber Hereditary Optic Neuropathy

23 Jun 2009

Abstract excerpt

PURPOSE: Leber hereditary optic neuropathy (LHON) is an inherited mitochondrial optic neuropathy characterized by bilateral, severe loss of central vision. In this study, the first formal assessment was conducted of visual disability in affected and unaffected individuals from molecularly confirmed LHON pedigrees. METHODS: Four hundred two LHON carriers--196 affected and 206 unaffected--from 125 genealogically...

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Drug-Induced Ocular Toxicity
Mitochondrial Function and Pathology
Retinal Development and Disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19255150
DOI: 10.1167/iovs.08-3166

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