Article
Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis.
Arthritis and rheumatism - 1 Mar 2009
Albers H M, Kurreeman F A S, Stoeken-Rijsbergen G, Brinkman D M C, Kamphuis S S M, van Rossum M A J, Girschick H J, Wouters C, Saurenmann R K, Hoppenreijs E, Slagboom P, Houwing-Duistermaat J J, Verduijn W, Huizinga T W J, Ten Cate R, Toes R E M, Schilham M W
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is characterized by chronic arthritis and an autoimmune etiology. In several autoimmune diseases, including rheumatoid arthritis (RA), an association with the 4q27 locus has been reported. We undertook this study to investigate the possible role of the 4q27 locus in JIA. METHODS: A case-control association study was conducted, with a total of 655 Caucasian JIA...
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