The Will-o'-the-Wisp of Genetics — Hunting for the Azoospermia Factor Gene

Abstract excerpt

It has been known for decades that the Y chromosome carries genes required for spermatogenesis and male fertility. But it has been frustratingly difficult to pin down the relevant genes, to such an extent that a finding reported by Luddi et al.1 in this issue of the Journal — that the ubiquitin-specific peptidase 9, Y-linked gene (USP9Y) is not essential for normal spermatogenesis — represents a noteworthy...

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