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Article

X-linked hypophosphatemic rickets and craniosynostosis.

The Journal of craniofacial surgery - 1 Mar 2009

Murthy Ananth S

Abstract excerpt

Bone mineralization is possible via complex interactions among fibroblast growth factor 23 (FGF23), phosphate-regulating gene with homologies to endopeptidases on the X-chromosome (PHEX), and matrix extracellular phosphoglycoprotein. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets. X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to PHEX Phosphate Regulating Neutral Endopeptidase

Source

Identifiers

PMID: 19242361
DOI: 10.1097/SCS.0b013e31819b9868

Genes

FGF23
PHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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X-linked hypophosphatemic rickets and craniosynostosis.PMID 19242361Read ↗

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