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Article

Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans.

The Journal of infectious diseases - 15 Mar 2009

Haas David W, Gebretsadik Tebeb, Mayo Gail, Menon Usha N, Acosta Edward P, Shintani Ayumi, Floyd Michael, Stein C Michael, Wilkinson Grant R

Abstract excerpt

BACKGROUND: Polymorphisms in CYP2B6 affect the steady-state plasma concentrations of nevirapine and efavirenz. In many resource-limited countries, a single dose of nevirapine has been widely prescribed to pregnant women at delivery, to reduce mother-to-child transmission of human immunodeficiency...

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Source

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Identifiers

PMID: 19239339
DOI: 10.1086/597125
PMCID: PMC2784690

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19239339-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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