Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of chondrocytic phenotype by micro RNA 18a: involvement of Ccn2/Ctgf as a major target gene.

FEBS letters - 18 Mar 2009

Ohgawara Toshihiro, Kubota Satoshi, Kawaki Harumi, Kondo Seiji, Eguchi Takanori, Kurio Naito, Aoyama Eriko, Sasaki Akira, Takigawa Masaharu

Abstract excerpt

We searched for miRNAs that were down-regulated in chondrocytic cells and predicted to target CCN2/connective tissue growth factor (CCN2/CTGF) that promotes endochondral ossification. Among them, expression of miR-18a was most strongly repressed in chondrocytic cells. Reporter gene analysis confi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chickens
Share to Chondrocytes
Share to Chondrogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connective Tissue Growth Factor

Share to HeLa Cells

Share to MicroRNAs

Share to Regulatory Elements, Transcriptional

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 19233176
DOI: 10.1016/j.febslet.2009.02.025

Genes

CCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19233176-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of chondrocytic phenotype by micro RNA 18a: involvement of Ccn2/Ctgf as a major target gene.PMID 19233176Read ↗

MicroRNA-337 is associated with chondrogenesis through regulating TGFBR2 expressionSemantic proximity Read ↗

Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritisSemantic proximity Read ↗

lncRNA ADAMTS9-AS2 Controls Human Mesenchymal Stem Cell Chondrogenic Differentiation and Functions as a ceRNASemantic proximity Read ↗

Long noncoding RNA DANCR regulates miR-1305 -Smad 4 axis to promote chondrogenic differentiation of human synovium-derived mesenchymal stem cellsSemantic proximity Read ↗

Matrilin-3 as a putative effector of C-type natriuretic peptide signaling during TGF-β induced chondrogenic differentiation of mesenchymal stem cellsSemantic proximity Read ↗

The circCRIM1–miR-320c–MMP16 Axis: A Regulator of Cartilage Differentiation and Homeostasis in Osteoarthritis with Therapeutic PotentialSemantic proximity Read ↗

Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 Pathway.Semantic proximity Read ↗

miRNAs control tracheal chondrocyte differentiation.Semantic proximity Read ↗

Roles of micro<scp>RNA</scp>s in prenatal chondrogenesis, postnatal chondrogenesis and cartilage‐related diseasesSemantic proximity Read ↗

microRNA-140 Targets RALA and Regulates Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Translational Enhancement of SOX9 and ACANSemantic proximity Read ↗

miR-1/206 down-regulates splicing factor Srsf9 to promote myogenesisSemantic proximity Read ↗

Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.