Article
miRNAs control tracheal chondrocyte differentiation.
Developmental biology - 1 Dec 2011
Gradus Ben, Alon Ilana, Hornstein Eran
Abstract excerpt
The specific program that enables the stereotypic differentiation of specialized cartilages, including the trachea, is intrinsically distinct from the program that gives rise to growth plate hypertrophic chondrocytes. For example, Snail1 is an effector of FGF signaling in growth plate pre-hypertrophic chondrocytes, but it derails the normal program of permanent chondrocytes, repressing the transcription of...
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