Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality.

Abstract excerpt

The function of an organ relies upon the proper relative proportions of its individual operational components. For example, effective embryonic circulation requires the appropriate relative sizes of each of the distinct pumps created by the atrial and ventricular cardiac chambers. Although the differences between atrial and ventricular cardiomyocytes are well established, little is known about the mechanisms...

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