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Article

Polymorphism of the long polyglutamine tract in the human androgen receptor influences craving of men in alcohol withdrawal.

Psychoneuroendocrinology - 1 Aug 2009

Lenz Bernd, Jacob Claudia, Frieling Helge, Jacobi Andrea, Hillemacher Thomas, Muschler Marc, Watson Kathryn, Kornhuber Johannes, Bleich Stefan

Abstract excerpt

Until recently, genetic mechanisms influencing craving in alcohol withdrawal were poorly understood. Studies show that alcoholism is associated with dysregulation of sexual hormones. The androgen receptor is encoded by the trinucleotide repeat CAG. Long repeat regions have been shown to inhibit interactions between the androgen receptor and different co-activators. The aim of the present study was to determine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19231085
DOI: 10.1016/j.psyneuen.2009.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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