Article
Amniotic fluid insulin-like growth factor binding protein 3 concentration as early indicator of fetal growth restriction.
European journal of obstetrics, gynecology, and reproductive biology - 1 May 2009
Murisier-Petetin Geraldine, Gremlich Sandrine, Damnon Francoise, Reymondin Danielle, Hohlfeld Patrick, Gerber Stefan
Abstract excerpt
OBJECTIVE: Insulin-like growth factor-I (IGF-I) is an important regulator of fetal growth and its bioavailability depends on insulin-like growth factor binding proteins (IGFBPs). Genes coding for IGF-I and IGFBP3 are polymorphic. We hypothesized that either amniotic fluid protein concentration at the beginning of the second trimester or genotype of one of these two genes could be predictive of abnormal fetal...
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