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Article

Genetic and epigenetic variability in the gene for IGFBP-3 (IGFBP3): correlation with serum IGFBP-3 levels and growth in short children born small for gestational age.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Jun 2009

van der Kaay D C M, Hendriks A E J, Ester W A, Leunissen R W J, Willemsen R H, de Kort S W K, Paquette J R, Hokken-Koelega A C S, Deal C L

Abstract excerpt

CONTEXT: IGF-I and IGFBP-3 play a central role in fetal and postnatal growth and levels are low in short SGA children. The -202 A/C and -185 C/T SNPs are located near elements involved in directing IGFBP3 promoter activity and expression. Changes in promoter CpG methylation status affect transcri...

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Share to Epigenesis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Human Growth Hormone

Share to Infant, Small for Gestational Age

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Insulin-Like Growth Factor Binding Proteins

Share to Insulin-Like Growth Factor I

Source

Identifiers

PMID: 18929499
DOI: 10.1016/j.ghir.2008.08.010

Genes

IGFBP3
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18929499-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic and epigenetic variability in the gene for IGFBP-3 (IGFBP3): correlation with serum IGFBP-3 levels and growth in short children born small for gestational age.PMID 18929499Read ↗

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