Article
Likelihood ratio tests for maternal and fetal genetic effects on obstetric complications.
Genetic epidemiology - 1 Sept 2009
Chen Jinbo, Zheng Haitao, Wilson Melissa L
Abstract excerpt
It is well recognized that both maternal and fetal genes could contribute to susceptibility for obstetric complications. Logistic regression models are usually adopted to model the separate or joint action of maternal and fetal loci with case-control data. The standard likelihood ratio tests (LRTs) can be used to test the significance of appropriate odds ratio parameters. This method, although simple to...
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