Article
Evaluating the association of common APOA2 variants with type 2 diabetes.
BMC medical genetics - 13 Feb 2009
Duesing Konsta, Charpentier Guillaume, Marre Michel, Tichet Jean, Hercberg Serge, Balkau Beverley, Froguel Philippe, Gibson Fernando
Abstract excerpt
BACKGROUND: APOA2 is a positional and biological candidate gene for type 2 diabetes at the chromosome 1q21-q24 susceptibility locus. The aim of this study was to examine if HapMap phase II tag SNPs in APOA2 are associated with type 2 diabetes and quantitative traits in French Caucasian subjects. METHODS: We genotyped the three HapMap phase II tagging SNPs (rs6413453, rs5085 and rs5082) required to capture the...
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