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Article

A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction.

Journal of virology - 1 May 2009

Moore Martin L, Chi Michael H, Luongo Cindy, Lukacs Nicholas W, Polosukhin Vasiliy V, Huckabee Matthew M, Newcomb Dawn C, Buchholz Ursula J, Crowe James E, Goleniewska Kasia, Williams John V, Collins Peter L, Peebles R Stokes

Abstract excerpt

Respiratory syncytial virus (RSV) is the leading cause of respiratory failure and viral death in infants. Abundant airway mucus contributes to airway obstruction in RSV disease. Interleukin-13 (IL-13) is a mediator of pulmonary mucus secretion. It has been shown that infection of BALB/c mice with...

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Identifiers

PMID: 19211758
DOI: 10.1128/JVI.01853-08
PMCID: PMC2668460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19211758-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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