Article
Family-based association analysis of S100A8 genetic polymorphisms with aggressive periodontitis.
Journal of periodontal research - 1 Apr 2009
Ren X Y, Xu L, Meng H X, Zhao H S, Lu R F, Chen Z B, Feng X H, Shi D, Zhang L, Tian Y
Abstract excerpt
BACKGROUND AND OBJECTIVE: It is known that S100A8, a member of the S100 calcium-binding protein family, is associated with inflammatory diseases, including periodontitis. Our previous population-based study found an association between two polymorphisms, rs3795391 (A > G) and rs3806232 (A > G), in the upstream region of the S100A8 gene and aggressive periodontitis (AgP) in Chinese people. Based on those results,...
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