Article
Detecting selective sweeps: a new approach based on hidden markov models.
Genetics - 1 Apr 2009
Boitard Simon, Schlötterer Christian, Futschik Andreas
Abstract excerpt
Detecting and localizing selective sweeps on the basis of SNP data has recently received considerable attention. Here we introduce the use of hidden Markov models (HMMs) for the detection of selective sweeps in DNA sequences. Like previously published methods, our HMMs use the site frequency spectrum, and the spatial pattern of diversity along the sequence, to identify selection. In contrast to earlier...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
